Comparative study of therapeutic programmes for tuberculosis, from data from the Public Department of Infectious Diseases of the city of Caxias do Sul

Authors

  • Francie Bueno Universidade de Caxias do Sul
  • Tathiane Andréa Klanovicz Universidade de Caxias do Sul
  • Luciana Mello de Oliveira Pontifícia Universidade Católica do Rio Grande do Sul
  • Claudia Wollhein Universidade de Caxias do Sul
  • Patricia Regina Araujo Universidade de Caxias do Sul
  • Tarcio Jovani Laurini Prefeitura de Caxias do Sul

DOI:

https://doi.org/10.24302/sma.v6i2.1299

Abstract

The aims of the present study were to assess treatment with tuberculostatics to verify the drop out rate in therapeutic programmes (2RHZ/4RH and 2RHZE/4RH), and to identify predictive factors associated to drop out of treatment. For this purpose, data gathered from literature and those made available by the local Public Department of Infectious Diseases of the city of Caxias do Sul in the 2011-2013 period were used. Pearson's chi-squared test or Fisher's exact test have been used to compare and associate the outcome of the treatment and the variables. The therapeutic programmes assessed in this study did not meet the WHO targets for tuberculosis control. The predictive factors for dropping out of treatment were: male, age between 20-39 years old, low level of education, new case, and presence of comorbidities. Out of these factors, the ones that resulted statistically significant when associated to the outcome of the treatment were admission (new case) and presence of comorbidities. In order to achieve effective tuberculosis control, it is necessary to reduce the factors of treatment drop out.

Keyword: Tuberculosis. Drop out of treatment. 2RHZ/4RH. 2RHZE/4RH.

Author Biographies

  • Francie Bueno, Universidade de Caxias do Sul
    Centro de Ciencias biologicas e da Saude, Curso de Farmácia
  • Tathiane Andréa Klanovicz, Universidade de Caxias do Sul
    Centro de Ciências biológicas e da Saúde, Curso de Farmácia
  • Luciana Mello de Oliveira, Pontifícia Universidade Católica do Rio Grande do Sul

    Curso de Farmácia

  • Claudia Wollhein, Universidade de Caxias do Sul
    Centro de Ciências Biológicas e da Saúde, Curso de Farmácia
  • Patricia Regina Araujo, Universidade de Caxias do Sul
    Centro de Ciências Biológicas e da Saúde, Curso de Farmácia
  • Tarcio Jovani Laurini, Prefeitura de Caxias do Sul
    Secretaria Municipal de Saude, Prefeitura de Caxias do Sul RS

Published

2017-12-20

Issue

Section

Artigos

How to Cite

1.
Bueno F, Klanovicz TA, Oliveira LM de, Wollhein C, Araujo PR, Laurini TJ. Comparative study of therapeutic programmes for tuberculosis, from data from the Public Department of Infectious Diseases of the city of Caxias do Sul. Saúde e meio ambient.: rev. interdisciplin. [Internet]. 2017 Dec. 20 [cited 2025 Jul. 6];6(2):39-52. Available from: https://www.periodicos.unc.br/index.php/sma/article/view/1299